Search on: ISOLEUCYL(5)-ANGIOTENSIN II 
Descriptors Found: 1
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Descriptor English:   Angiotensin II 
Descriptor Spanish:   Angiotensina II 
Descriptor Portuguese:   Angiotensina II 
Synonyms English:   5-L-Isoleucine Angiotensin II
ANG-(1-8)Octapeptide
Angiotensin II, Isoleucine(5)-
Angiotensin II, Valine(5)-
Angiotensin-(1-8) Octapeptide
Isoleucine(5)-Angiotensin
Isoleucyl(5)-Angiotensin II
Valyl(5)-Angiotensin II
5 L Isoleucine Angiotensin II
Angiotensin II, 5-L-Isoleucine
Angiotensin II, Ile(5)-
Angiotensin II, Val(5)-  
Tree Number:   D06.472.699.094.078
D12.644.400.070.078
D12.644.456.073.041
D12.644.548.058.078
D12.776.631.650.070.078
D23.469.050.050.050
Definition English:   An octapeptide that is a potent but labile vasoconstrictor. It is produced from angiotensin I after the removal of two amino acids at the C-terminal by ANGIOTENSIN CONVERTING ENZYME. The amino acid in position 5 varies in different species. To block VASOCONSTRICTION and HYPERTENSION effect of angiotensin II, patients are often treated with ACE INHIBITORS or with ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS. 
Pharmacological Action:   Vasoconstrictor Agents
 
See Related English:   Renin-Angiotensin System
 
History Note English:   1974(1963); for ANGIOTENSIN II, ILE(5)- use ANGIOTENSIN II (NM) 1974-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   22334 
Unique Identifier:   D000804 

Occurrence in VHL: 		 

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